Association of high maternal triglyceride levels early and late in pregnancy with adverse outcomes: A retrospective cohort study

نویسندگان

چکیده

•It is unclear whether persistently high mTG during gestation has worse outcomes.•Persistently increased the risks of preeclampsia, gestational diabetes mellitus, and large for age.•Elevated in early pregnancy may be critical predicting adverse outcomes. BackgroundExcess maternal triglyceride (mTG) exposure or late increases However, it inconclusive whole more negative associations.ObjectiveTo explore levels from to further risk outcomes.MethodsWe included 12,715 women who had a singleton birth underwent routine serum lipid screenings both (9-13 weeks) (28–42 May 2018 July 2019 university-based maternity center. Risks mellitus (GDM), preterm delivery, small/large age (LGA) were estimated.ResultsElevated associated with delivery (AOR, 1.52; 95% CI, 1.21 1.90), preeclampsia (1.75; 1.29 2.36), (1.95; 1.69 2.25), LGA (1.28; 1.12 1.46). Compared those low 1st 3rd trimesters, (2.53; 1.66 3.84), GDM (1.97; 1.57 2.47), (1.68; 1.37 2.07). only slightly when compared trimester alone (1.34, 1.01 1.77).ConclusionsElevated not could crucial factor These results suggest importance preventions pregnancy, which help improve Excess associations. To We estimated. Elevated 1.77).

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ژورنال

عنوان ژورنال: Journal of Clinical Lipidology

سال: 2021

ISSN: ['1933-2874', '1876-4789']

DOI: https://doi.org/10.1016/j.jacl.2020.10.001